Assam Journal of Internal Medicine

CASE REPORT
Year
: 2021  |  Volume : 11  |  Issue : 2  |  Page : 48--49

A case of ovarian hyperstimulation syndrome with diffuse cortical necrosis


Sweety Kakoti, Dhruvajyoti Choudhury, Tonmoy Das 
 Department of Nephrology, Apollo Hospital Guwahati, Ganeshguri, Guwahati, Assam, India

Correspondence Address:
Dr. Sweety Kakoti
Department of Nephrology, Apollo Hospital Guwahati, Ganeshguri, Guwahati, Assam
India

Ovarian hyperstimulation syndrome is an iatrogenic, serious complication of controlled ovarian hyperstimulation, usually self-limited, but occasionally life threatening and typically occurs with gonadotropin. A 32-year-old married female [Para 0+1, 30 weeks (intra-uterine death)—2016], who underwent ovum pick up procedure for secondary infertility, presented to the Department of Nephrology, Apollo Hospital, Guwahati with the complaints of pain in the abdomen, anuria, breathing difficulty, bleeding per vagina on the next day. On investigating the case, the patient had thrombocytopenia, leucocytosis, anemia, normal morphology in peripheral blood smear, raised inflammatory markers, hepatic transaminases, lactate dehydrogenase, and rapidly progressive renal failure, metabolic acidosis with negative serological markers for connective tissue disease. Radio imaging suggested bilaterally enlarged ovaries with multiple hemorrhagic cysts, pleural effusion, and ascites. Ultrasound showed normal sized kidneys with increased echotexture and hypoechoeic cortical rim. Renal biopsy showed diffuse renal cortical necrosis. Supportive management started with a target to correct volume depletion, monitoring, and electrolyte abnormalities. Patient was hemodynamically stabilised and discharged on thrice weekly maintenance dialysis.


How to cite this article:
Kakoti S, Choudhury D, Das T. A case of ovarian hyperstimulation syndrome with diffuse cortical necrosis.Assam J Intern Med 2021;11:48-49


How to cite this URL:
Kakoti S, Choudhury D, Das T. A case of ovarian hyperstimulation syndrome with diffuse cortical necrosis. Assam J Intern Med [serial online] 2021 [cited 2022 Jan 19 ];11:48-49
Available from: http://www.ajimedicine.com/article.asp?issn=2278-8239;year=2021;volume=11;issue=2;spage=48;epage=49;aulast=Kakoti;type=0